Octagonal Blender – Operation and Cleaning Guide

A quick guide to learning how to operate and clean the Octagonal Blender used in the tablet manufacturing industry.

Start Up Operation

1. Check the overall cleanliness of the machine.
2. Place the materials to be blended near the machine.
3. Load the material and set the timer as per the product’s BMR.
4. Set the RPM as per the product specification in the BMR. Switch the “ON” button in the main and run the machine.

Shutdown

1. Shut down the main switch.
2. Inform maintenance to switch off the main power supply from the panel board in the service area.

Cleaning (Days End Cleaning)

1. Remove excess, stuck materials using a vacuum cleaner, lint free cloth or duster.
2. Disassemble the machine in the sequence as provided below:
   • Back lid
   • Charging lid
   • Single bolt baffle
3. Clean the dismantled parts with lint free cloth or vacuum cleaner.
4. Clean the machine and disassemble other parts using a lint free cloth.
5. Clean the processing area as per the SOP.
6. Assemble the machine.
7. Once done, place “cleaned” label to the equipment.
8. Document and log the cleaning in the log card.

Cleaning during Batch Changeover (Same Product of Ascending Potency)

1. Remove excess, stuck materials using a vacuum cleaner, lint free cloth or duster.
2. Disassemble the machine in the sequence as provided below:
   • Back lid
   • Charging lid
   • Single bolt baffle
3. Clean the dismantled parts with lint free cloth or vacuum cleaner.
4. Clean the machine and disassemble other parts using a lint free cloth.
5. Clean the processing area as per the SOP.
6. Assemble the machine.
7. Once done, place “cleaned” label to the equipment.
8. Document and log the cleaning in the log card.

Cleaning at the time of Changeover/Same product of Descending Potency (Preventative Maintenance of Contact Parts)

1. Remove excess, stuck materials using a vacuum cleaner, lint free cloth or duster.
2. Disassemble the machine in the sequence as provided below:
   1. Back lid
   2. Charging lid
   3. Single bolt baffle
3. Clean the exterior of the equipment with vacuum cleaner and lint free cloth.
4. Wash the dismantled part with running water followed by rinsing with purified water.
5. Wipe all the parts with 2% NaOH solution using cotton duster and allow it to remain for five to ten minutes.
6. Clean all with running potable water using a cotton duster.
7. Rinse all with enough purified water.
8. Collect the final rinse in a conical flask with label and send to the QA department.
9. Dry the equipment parts using a dryer.
10. Assemble the equipment.
11. Once cleaning is done, place a “cleaned” label on the equipment.
12. Document the cleaning details in the equipment log.